Is Upstream Bio, Inc. (UPB) halal? Not Halal. Based on AAOIFI screening, Upstream Bio, Inc. passes the business activity screen but fails financial ratio screens with a compliance score of 0/100 (Grade: F).

UPB — Is Upstream Bio, Inc. Halal?
Not HalalUpstream Bio, Inc.
$7.25
-10.27%
About Upstream Bio, Inc.
Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.
Sector: Healthcare · Industry: Biotechnology
Shariah Compliance Status
Based on AAOIFI screening standards
Non-Compliant
Fails Shariah screening
Business Activity Screen
PassedChecks if the business is involved in prohibited activities (alcohol, gambling, pork, conventional banking, etc.)
Financial Ratio Screen
FailedFinancial ratios must be below AAOIFI thresholds
Compliance History
Not Halal — unchanged since Jun 2026.
No status changes recorded since we began tracking.
Tracked since Jun 2026. Updates automatically on each re-screen.
Financial Overview
Market Cap
394.5M
Price
$7.25
Sector
Healthcare
Industry
Biotechnology
Halal Alternatives in Healthcare
This stock is not Shariah-compliant. Here are halal alternatives from the same sector, ranked by compliance score:
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Disclaimer: This screening is for informational purposes only and does not constitute financial, legal, or religious advice. Compliance is evaluated using AAOIFI financial standards (debt, deposits, and prohibited income ratios) and publicly available data. Ethical, political, social, or environmental considerations are outside the scope of this screening. Individual scholars and methodologies may differ. Always consult a qualified Islamic finance advisor before making investment decisions.
