Compliance Status

Halal

Screened on Oct 15, 2026 · AAOIFI Standard 21

B

Acceptable

62Score

Is Puma Biotechnology, Inc. (PBYI) halal? Halal. Based on AAOIFI screening, Puma Biotechnology, Inc. passes both qualitative (business activity) and quantitative (financial ratio) screens with a compliance score of 62/100 (Grade: B).

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HalalScreener rates Puma Biotechnology, Inc. (PBYI) Halal, 62/100, grade B under AAOIFI Standard 21, screened Oct 15, 2026. Source: https://halalscreener.app/en/stock/PBYI

Business activity

What the company sells is permissible.

Passed

Company debt

Within the limit

How much the company borrows, compared to its total value. AAOIFI allows up to 30%.

18.6% of 30.0% limit
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Screened according to AAOIFI Standard 21

What this means for you

You can own PBYI

It passes both the business activity and financial ratio screens under AAOIFI Standard 21.

Purification amount is Pro

We have screened PBYI's prohibited income, but the exact share you would need to purify is part of Pro.

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Puma Biotechnology, Inc.

PBYI: Is Puma Biotechnology, Inc. Halal?

Puma Biotechnology, Inc.

NASDAQHealthcareUS

$9.83

Market Cap: 507.4M

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About Puma Biotechnology, Inc.

Puma Biotechnology, Inc. is a biopharmaceutical company dedicated to the global development and commercialization of treatments aimed at advancing cancer care. Its lead drug candidate, orally administered neratinib (PB272), targets a range of indications. These include patients with early-stage HER2-overexpressed/amplified breast cancer, as well as adults suffering from advanced or metastatic HER2-positive breast cancer when used in combination with capecitabine. Furthermore, PB272 is being explored for solid tumors exhibiting HER2 mutations. The company holds a licensing agreement with Pfizer, Inc. for this drug and has established sub-licensing partnerships with Specialised Therapeutics Asia Pte Ltd., CANbridge BIOMED Limited, Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. Established in 2010, Puma Biotechnology maintains its headquarters in Los Angeles, California.

Sector: Healthcare · Industry: Biotechnology

Shariah Compliance Status

AAOIFI Standard 21Updated Oct 15, 2026

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Screened according to AAOIFI Standard 21

Compliance History

  1. Halalnow

    since Jun 2026

  2. Doubtful

    until the change above

  3. Not Halal

    until the change above

Tracked since Jun 2026. Updates automatically on each re-screen.

Fiscal: Q2 2026Data source: EDGAR
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Frequently Asked Questions

Is Puma Biotechnology, Inc. (PBYI) halal to invest in?
Based on AAOIFI Standard 21 screening, Puma Biotechnology, Inc. (PBYI) is rated Halal with a compliance grade of B (Acceptable). It passes both the business activity screen (no primary involvement in prohibited sectors) and the quantitative financial ratio screen (debt, interest deposits, and prohibited income all below AAOIFI thresholds).
Why did Puma Biotechnology, Inc. get a B compliance rating?
Puma Biotechnology, Inc. (PBYI) received a grade of B (Acceptable) based on three AAOIFI Standard 21 financial ratios: debt-to-market-cap of 18.6% (limit 30%). The grade reflects the margin of safety across all three ratios relative to their thresholds.
What could change Puma Biotechnology, Inc.'s Shariah verdict?
Puma Biotechnology, Inc.'s verdict is re-evaluated at each annual re-screen. Three events could change it: (1) the debt-to-market-cap ratio crossing 30%, typically from new debt issuance or a major drop in share price; (2) interest-bearing deposits exceeding 30% of market cap; or (3) prohibited revenue (alcohol, gambling, conventional finance, etc.) exceeding 5% of total revenue. Verdict flips are tracked in the compliance history section above.
How often is Puma Biotechnology, Inc. re-screened for Shariah compliance?
Puma Biotechnology, Inc. (PBYI) is re-screened annually using the most recent full-year financial data from SEC filings. HalalScreener also triggers an on-demand re-screen whenever the stored data is more than 7 days old, ensuring the ratios reflect the latest available financial statements. Last screened: Oct 15, 2026.

Screened according to AAOIFI Standard No. 21 · For informational purposes only. Consult a qualified Islamic finance advisor before investing.

Disclaimer: This screening is for informational purposes only and does not constitute financial, legal, or religious advice. Compliance is evaluated using AAOIFI financial standards (debt, deposits, and prohibited income ratios) and publicly available data. Ethical, political, social, or environmental considerations are outside the scope of this screening. Individual scholars and methodologies may differ. Always consult a qualified Islamic finance advisor before making investment decisions.