Compliance Status

Halal

Screened on Oct 7, 2026 · AAOIFI Standard 21

B

Acceptable

67Score

Is Cue Biopharma, Inc. (CUE) halal? Halal. Based on AAOIFI screening, Cue Biopharma, Inc. passes both qualitative (business activity) and quantitative (financial ratio) screens with a compliance score of 67/100 (Grade: B).

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HalalScreener rates Cue Biopharma, Inc. (CUE) Halal, 67/100, grade B under AAOIFI Standard 21, screened Oct 7, 2026. Source: https://halalscreener.app/en/stock/CUE

Business activity

What the company sells is permissible.

Passed

Company debt

Well clear of the limit

How much the company borrows, compared to its total value. AAOIFI allows up to 30%.

5.4% of 30.0% limit
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Screened according to AAOIFI Standard 21

What this means for you

You can own CUE

It passes both the business activity and financial ratio screens under AAOIFI Standard 21.

Purification amount is Pro

We have screened CUE's prohibited income, but the exact share you would need to purify is part of Pro.

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Cue Biopharma, Inc.

CUE: Is Cue Biopharma, Inc. Halal?

Cue Biopharma, Inc.

NASDAQHealthcareUS

$27.66

Market Cap: 200.9M

Screened on a market cap of 163.5M

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About Cue Biopharma, Inc.

Cue Biopharma, Inc. is a clinical-stage biopharmaceutical enterprise focused on creating biological therapies. Its central objective is the precise manipulation of the human immune system to address a spectrum of severe conditions, such as various cancers, chronic infectious diseases, and autoimmune disorders. The company's leading investigational therapeutic is CUE-101, a specialized fusion protein biologic. This candidate is currently advancing through Phase 1b clinical trials, engineered to specifically identify and activate antigen-specific T cells involved in cancers originating from human papillomavirus. Beyond its flagship program, Cue Biopharma is also developing a range of other innovative platforms: CUE-102, another fusion protein biologic designed to stimulate specific T cells to combat cancer; CUE-103, an Immuno-STAT from the CUE-100 series, which is developed to target the KRAS G12V mutation relevant in diseases like colorectal, lung, and pancreatic cancers; CUE-200, which concentrates on cell surface receptors such as CD80 and/or 4-1BBL to counteract T cell exhaustion often seen in chronic infections; and the CUE-300 and CUE-400 frameworks, conceptual platforms aimed at treating diverse autoimmune conditions. Cue Biopharma maintains key strategic alliances, including collaborations with Merck Sharp & Dohme Corp. for the research and development of its unique biologics targeting autoimmune indications, with LG Chem Life Sciences for advancing Immuno-STATs in the field of oncology, and with the Albert Einstein College of Medicine. The company, founded in 2014, was initially known as Imagen Biopharma, Inc. before adopting its current name, Cue Biopharma, Inc., in October 2016. It is headquartered in Cambridge, Massachusetts.

Sector: Healthcare · Industry: Biotechnology

Shariah Compliance Status

AAOIFI Standard 21Updated Oct 7, 2026

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Screened according to AAOIFI Standard 21

Compliance History

  1. Halalnow

    since Oct 2026

  2. Doubtful

    until the change above

  3. Not Halal

    until the change above

Tracked since Aug 2026. Updates automatically on each re-screen.

Fiscal: Q2 2026Data source: EDGAR
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Frequently Asked Questions

Is Cue Biopharma, Inc. (CUE) halal to invest in?
Based on AAOIFI Standard 21 screening, Cue Biopharma, Inc. (CUE) is rated Halal with a compliance grade of B (Acceptable). It passes both the business activity screen (no primary involvement in prohibited sectors) and the quantitative financial ratio screen (debt, interest deposits, and prohibited income all below AAOIFI thresholds).
Why did Cue Biopharma, Inc. get a B compliance rating?
Cue Biopharma, Inc. (CUE) received a grade of B (Acceptable) based on three AAOIFI Standard 21 financial ratios: debt-to-market-cap of 5.4% (limit 30%). The grade reflects the margin of safety across all three ratios relative to their thresholds.
What could change Cue Biopharma, Inc.'s Shariah verdict?
Cue Biopharma, Inc.'s verdict is re-evaluated at each annual re-screen. Three events could change it: (1) the debt-to-market-cap ratio crossing 30%, typically from new debt issuance or a major drop in share price; (2) interest-bearing deposits exceeding 30% of market cap; or (3) prohibited revenue (alcohol, gambling, conventional finance, etc.) exceeding 5% of total revenue. Verdict flips are tracked in the compliance history section above.
How often is Cue Biopharma, Inc. re-screened for Shariah compliance?
Cue Biopharma, Inc. (CUE) is re-screened annually using the most recent full-year financial data from SEC filings. HalalScreener also triggers an on-demand re-screen whenever the stored data is more than 7 days old, ensuring the ratios reflect the latest available financial statements. Last screened: Oct 7, 2026.

Screened according to AAOIFI Standard No. 21 · For informational purposes only. Consult a qualified Islamic finance advisor before investing.

Disclaimer: This screening is for informational purposes only and does not constitute financial, legal, or religious advice. Compliance is evaluated using AAOIFI financial standards (debt, deposits, and prohibited income ratios) and publicly available data. Ethical, political, social, or environmental considerations are outside the scope of this screening. Individual scholars and methodologies may differ. Always consult a qualified Islamic finance advisor before making investment decisions.