What is Prelude Therapeutics Incorporated's Shariah compliance score?

Prelude Therapeutics Incorporated (PRLD) has a Shariah compliance score of 0/100 (Grade: F, Non-Compliant). AAOIFI Standard No. 21 requires: (1) no primary involvement in prohibited activities like alcohol, gambling, or conventional banking, (2) debt-to-market-cap below 30%, (3) interest-bearing deposits below 30%, and (4) prohibited income below 5%.

Does Prelude Therapeutics Incorporated pass AAOIFI screening?

Prelude Therapeutics Incorporated (PRLD) does not pass AAOIFI Shariah screening. AAOIFI Standard No. 21 requires: (1) no primary involvement in prohibited activities like alcohol, gambling, or conventional banking, (2) debt-to-market-cap below 30%, (3) interest-bearing deposits below 30%, and (4) prohibited income below 5%. PRLD's debt-to-market-cap is 6.4%.

How much purification is needed for Prelude Therapeutics Incorporated?

Muslim investors purify the portion of dividends and realized gains that comes from non-permissible income by donating it to charity. HalalScreener's purification calculator at halalscreener.app/en/purification computes the percentage and amount for Prelude Therapeutics Incorporated (PRLD) using the latest financial data.

Where can I screen Prelude Therapeutics Incorporated for Shariah compliance for free?

HalalScreener (halalscreener.app) offers free Shariah compliance screening for Prelude Therapeutics Incorporated (PRLD) and 8,200+ securities. US-listed stocks and ETFs are screened under AAOIFI Standard No. 21. Bursa Malaysia securities carry the Securities Commission Malaysia's official status. Coins are screened separately, under published scholarly opinion. The verdict is free, with no credit card or signup required for basic screening. The compliance grade, score, and debt ratio are free too; the full ratio breakdown is part of Pro.

PRLDNot HalalF

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PRLD: Is Prelude Therapeutics Incorporated Halal?

Prelude Therapeutics Incorporated

NASDAQHealthcareUS

$3.88

Market Cap: 220.6M

Screened on a market cap of 276.1M

Compliance Status

Not Halal

Screened on Sep 23, 2026 · AAOIFI Standard 21

Non-Compliant

0Score

Is Prelude Therapeutics Incorporated (PRLD) halal? Not Halal. Based on AAOIFI screening, Prelude Therapeutics Incorporated passes the business activity screen but fails financial ratio screens with a compliance score of 0/100 (Grade: F).

Quote this verdict

HalalScreener rates Prelude Therapeutics Incorporated (PRLD) Not Halal, 0/100, grade F under AAOIFI Standard 21, screened Sep 23, 2026. Source: https://halalscreener.app/en/stock/PRLD

AvoidBorderlineClean

Business activity

What the company sells is permissible.

Passed

Company debt

Well clear of the limit

How much the company borrows, compared to its total value. AAOIFI allows up to 30%.

6.4% of 30.0% limit

PRO DETAIL

The verdict above is final and free.

Pro members can verify every number behind it: interest-bearing deposits, prohibited income breakdown, and the full AAOIFI math.

Screened according to AAOIFI Standard 21

What this means for you

Most scholars advise not holding PRLD

It does not pass AAOIFI Shariah screening.

See halal alternatives from the same sector further down this page

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About Prelude Therapeutics Incorporated

Prelude Therapeutics, Inc. is a clinical-stage precision oncology company focused on identifying and developing innovative, targeted cancer treatments for patient populations with unmet medical needs. Its pipeline includes PRT543, currently undergoing Phase 1 clinical evaluation for certain solid tumors and myeloid malignancies. Another asset, PRT811, is also in Phase 1 trials, targeting various solid tumors, notably glioblastoma multiforme. The company is additionally progressing PRT1419, a potent and selective inhibitor of the anti-apoptotic protein; PRT2527, a powerful and highly kinome-selective CDK9 inhibitor; PRT-SCA2, which is in preclinical development for several genomically selected cancers; PRT3645, a brain-penetrant molecule that precisely and effectively targets CDK4/6; and PRT-K4, another preclinical compound for solid tumors. Founded in 2016, the firm's headquarters are located in Wilmington, Delaware.

Sector: Healthcare · Industry: Biotechnology

Why this does not pass

Interest-bearing deposits are over the 30% limit.

Screened under AAOIFI Standard 21. The exact figure behind this is part of Pro; the failing check and its limit are always free.

Shariah Compliance Status

AAOIFI Standard 21Updated Sep 23, 2026

See which ratio caused the failure.

See the exact debt ratio, interest income %, and prohibited revenue that caused the failure. Know before you sell or hold.

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Institutional-grade Shariah analysis

See why PRLD is rated Not Halal with institutional-grade analysis

PRO DETAIL

The verdict above is final and free.

Pro members can verify every number behind it: interest-bearing deposits, prohibited income breakdown, and the full AAOIFI math.

Screened according to AAOIFI Standard 21

Compliance History

Not Halal, unchanged since Aug 2026.

No status changes recorded since we began tracking.

Tracked since Aug 2026. Updates automatically on each re-screen.

Fiscal: Q2 2026Data source: EDGAR

Halal Alternatives in Healthcare

This stock is not Shariah-compliant. Here are halal alternatives from the same sector, ranked by compliance score:

BLTEA+

Belite Bio, Inc

$167.33

0001.KLA+

Supercomnet Technologies Bhd

$0.50

+0.01%

0002.KLA+

Kotra Industries Bhd

$3.85

+0.00%

0101.KLA+

TMC Life Sciences Bhd

$0.43

-0.01%

0155.KLA+

Malaysian Genomics Resource Centre Bhd

$0.35

+0.00%

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Frequently Asked Questions

Is Prelude Therapeutics Incorporated (PRLD) halal to invest in?

Prelude Therapeutics Incorporated (PRLD) is rated Not Halal under AAOIFI Standard 21 screening. It fails either the business activity screen (primary involvement in prohibited sectors such as conventional banking, alcohol, or gambling) or one of the quantitative financial ratio thresholds. Muslim investors should avoid or exit this position.

Why did Prelude Therapeutics Incorporated get a F compliance rating?

Prelude Therapeutics Incorporated (PRLD) received a grade of F (Non-Compliant) based on three AAOIFI Standard 21 financial ratios: debt-to-market-cap of 6.4% (limit 30%). The grade reflects the margin of safety across all three ratios relative to their thresholds.

What could change Prelude Therapeutics Incorporated's Shariah verdict?

Prelude Therapeutics Incorporated's verdict is re-evaluated at each annual re-screen. Three events could change it: (1) the debt-to-market-cap ratio crossing 30%, typically from new debt issuance or a major drop in share price; (2) interest-bearing deposits exceeding 30% of market cap; or (3) prohibited revenue (alcohol, gambling, conventional finance, etc.) exceeding 5% of total revenue. Verdict flips are tracked in the compliance history section above.

How often is Prelude Therapeutics Incorporated re-screened for Shariah compliance?

Prelude Therapeutics Incorporated (PRLD) is re-screened annually using the most recent full-year financial data from SEC filings. HalalScreener also triggers an on-demand re-screen whenever the stored data is more than 7 days old, ensuring the ratios reflect the latest available financial statements. Last screened: Sep 23, 2026.

Screened according to AAOIFI Standard No. 21 · For informational purposes only. Consult a qualified Islamic finance advisor before investing.

Disclaimer: This screening is for informational purposes only and does not constitute financial, legal, or religious advice. Compliance is evaluated using AAOIFI financial standards (debt, deposits, and prohibited income ratios) and publicly available data. Ethical, political, social, or environmental considerations are outside the scope of this screening. Individual scholars and methodologies may differ. Always consult a qualified Islamic finance advisor before making investment decisions.