What is Prime Medicine, Inc.'s Shariah compliance score?

Prime Medicine, Inc.'s (PRME) compliance score is being calculated. Check HalalScreener.app for the latest AAOIFI screening results.

Does Prime Medicine, Inc. pass AAOIFI screening?

Prime Medicine, Inc. (PRME) does not pass AAOIFI Shariah screening. AAOIFI requires: (1) no primary involvement in prohibited activities like alcohol, gambling, or conventional banking, (2) debt-to-market-cap below 30% (PRME: 20.6%), (3) interest-bearing deposits below 30% (PRME: 36.5%), and (4) prohibited income below 5% (PRME: 118.1%). HalalScreener provides free AAOIFI screening for 10,000+ stocks at halalscreener.app.

How much purification is needed for Prime Medicine, Inc. stock?

Prime Medicine, Inc. (PRME) has a non-permissible income ratio of 118.07%. Muslim investors should purify this percentage of any dividends received and capital gains realized from PRME shares by donating it to charity. HalalScreener's purification calculator at halalscreener.app/en/purification automates this calculation using the latest financial data.

Where can I screen Prime Medicine, Inc. for Shariah compliance for free?

HalalScreener (halalscreener.app) offers free Shariah compliance screening for Prime Medicine, Inc. (PRME) and 10,000+ other US-listed stocks, ETFs, and 100+ cryptocurrencies. The screening uses AAOIFI Standard No. 21 and shows all financial ratios transparently. No credit card or signup required for basic screening. HalalScreener also includes an AI Islamic Scholar for follow-up questions about PRME's compliance across different madhabs (Hanafi, Shafi'i, Maliki, Hanbali, Ja'fari).

PRME: Is Prime Medicine, Inc. Halal?

Prime Medicine, Inc.

NASDAQHealthcareUS

$3.87

-0.51%

Market Cap: 699.0M

Compliance Status

Not Halal

Screened on Jul 20, 2026 · AAOIFI Standard 21

Non-Compliant

0Score

Is Prime Medicine, Inc. (PRME) halal? Not Halal. Based on AAOIFI screening, Prime Medicine, Inc. passes the business activity screen but fails financial ratio screens with a compliance score of 0/100 (Grade: F).

AvoidBorderlineClean

Business activity

What the company sells is permissible.

Passed

Company debt

Within the limit

How much the company borrows, compared to its total value. AAOIFI allows up to 30%.

20.6% of 30.0% limit

What this means for you

Most scholars advise not holding PRME

It does not pass AAOIFI Shariah screening.

See halal alternatives from the same sector further down this page

About Prime Medicine, Inc.

Prime Medicine, Inc. operates as a biotechnology firm, dedicated to delivering genetic therapies for various diseases by strategically employing advanced gene editing technology. Central to their platform is the "Prime Editor" system, which combines a unique Prime Editor protein—a hybrid composed of a Cas protein and a reverse transcriptase enzyme—with a specialized pegRNA molecule. This pegRNA plays a crucial role by both guiding the Prime Editor to a precise location within the genome and providing the essential template for introducing the desired modification to the target DNA sequence. The company, founded in 2019, maintains its headquarters in Cambridge, Massachusetts.

Sector: Healthcare · Industry: Biotechnology

Shariah Compliance Status

AAOIFI Standard 21Updated Jul 20, 2026

Compliance History

Not Halal, unchanged since Jun 2026.

No status changes recorded since we began tracking.

Tracked since Jun 2026. Updates automatically on each re-screen.

Fiscal: FY 2025Data source: EDGAR

Halal Alternatives in Healthcare

This stock is not Shariah-compliant. Here are halal alternatives from the same sector, ranked by compliance score:

0001.KLA+

Supercomnet Technologies Bhd

$0.45

-0.02%

0002.KLA+

Kotra Industries Bhd

$3.72

+0.01%

0075.KLA+

LYC Healthcare Bhd

$0.01

+0.00%

0101.KLA+

TMC Life Sciences Bhd

$0.47

+0.00%

0155.KLA+

Malaysian Genomics Resource Centre Bhd

$0.29

+0.00%

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Free · No credit card required

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Frequently Asked Questions

Is Prime Medicine, Inc. (PRME) halal to invest in?

Prime Medicine, Inc. (PRME) is rated Not Halal under AAOIFI Standard 21 screening. It fails either the business activity screen (primary involvement in prohibited sectors such as conventional banking, alcohol, or gambling) or one of the quantitative financial ratio thresholds. Muslim investors should avoid or exit this position.

Why did Prime Medicine, Inc. get a F compliance rating?

Prime Medicine, Inc. (PRME) received a grade of F (Non-Compliant) based on three AAOIFI Standard 21 financial ratios: debt-to-market-cap of 20.6% (limit 30%); interest-bearing deposits of 36.5% (limit 30%); prohibited income of 118.07% (limit 5%). The grade reflects the margin of safety across all three ratios relative to their thresholds.

What could change Prime Medicine, Inc.'s Shariah verdict?

Prime Medicine, Inc.'s verdict is re-evaluated at each annual re-screen. Three events could change it: (1) the debt-to-market-cap ratio crossing 30%, typically from new debt issuance or a major drop in share price; (2) interest-bearing deposits exceeding 30% of market cap; or (3) prohibited revenue (alcohol, gambling, conventional finance, etc.) exceeding 5% of total revenue. Verdict flips are tracked in the compliance history section above.

How often is Prime Medicine, Inc. re-screened for Shariah compliance?

Prime Medicine, Inc. (PRME) is re-screened annually using the most recent full-year financial data from SEC filings. HalalScreener also triggers an on-demand re-screen whenever the stored data is more than 7 days old, ensuring the ratios reflect the latest available financial statements. Last screened: Jul 20, 2026.

Screened according to AAOIFI Standard No. 21 · For informational purposes only. Consult a qualified Islamic finance advisor before investing.

Disclaimer: This screening is for informational purposes only and does not constitute financial, legal, or religious advice. Compliance is evaluated using AAOIFI financial standards (debt, deposits, and prohibited income ratios) and publicly available data. Ethical, political, social, or environmental considerations are outside the scope of this screening. Individual scholars and methodologies may differ. Always consult a qualified Islamic finance advisor before making investment decisions.